Andrew McCutcheon launched an opposite field, walk off home run to lead off the bottom of the 12th inning as the Pittsburgh Pirates beat the Milwaukee Brewers 4-3 at PNC Park Tuesday night. McCutcheon's 5th homer of the season came on a 2-2 pitch from Mike Fiers. The Brewers took an early lead as Jean Segura hit a home run in the first inning. Ryan Braun and Nori Aoki each had three hits as Milwaukee built a 3-1 lead. Starter Kyle Lohse struggled with control, walking five in five and two thirds innings but he left with a 3-2 lead. The Pirates tied the game in the 8th off John Axford who gave up a single and RBI double to Russell Martin. The Brewers were held scoreless over the final seven innings by the Pittsburgh bullpen. Milwaukee (16-21) has fallen 8 and a half games behind division leading St. Louis. They'll send Yovani Gallardo against Wandy Rodriguez in game three of the four game series Wednesday night. Pre-game coverage begins at 5:30 PM on WTAQ.